| ncRNA name | hsa-miR-124 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB cell line Y79; RPE cell line ARPE-19 |
| Methods | qRT-PCR, transfection, MTT assay, flow cytometry, migration and invasion assay, luciferase reporter assay, Western blot |
| Expression pattern | down-regulated |
| Functional description | miR-124 suppression inhibited cell apoptosis and remarkably abolished the inhibitory effects of MALAT1 silence on cell viability, migration, and invasion. Slug was a target of miR-124 and regulated cell viability, migration, invasion, and apoptosis in Y79 cells. |
| PubMed ID | 28550678 |
| Year | 2018 |
| Title | Knockdown of Long Noncoding RNA (lncRNA) Metastasis-Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Inhibits Proliferation, Migration, and Invasion and Promotes Apoptosis by Targeting miR-124 in Retinoblastoma. |
| Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.